Behind the Scenes at SLAS2023: Special Interview with Davide Gianni

Recorded onsite at SLAS2023 in San Diego, California, podcast Editor Rob Howes speaks with Davide Gianni, Ph.D. (AstraZeneca) to learn more about Gianni's protocol paper, "A multi-parametric high throughput assay for detecting beta-cell proliferation in dispersed primary islets," published in Volume 28, Issue 2 of SLAS Discovery. 

Here Davide describes the development of a 384-well plate-based multi-parametric imaging assay designed to capture ex vivo primary islet proliferation, a known pathology related to Diabetes. The development of this assay allows for the positive identification of compounds that can selectively enhance islet beta-cell proliferation and reverse this known disease phenotype. 

For more information about SLAS Discovery, visit https://slas-discovery.org/