Behind the Article: A Perspective on the Discovery of Enzyme Activators

Welcome to the SLAS Discovery Author Insights podcast! Today we are joined by Antonia Turberville and Geoffrey A. Holdgate to discuss their recent perspective article titled "A perspective on the discovery of enzyme activators". This article sheds light on the largely under-explored area of enzyme activation in drug discovery.

Despite the successful application of enzyme activators in various therapeutic interventions, the field remains under-represented and poorly exploited. Antonia and Geoffrey delve into the challenges of hit identification for enzyme activation, as well as their perspectives on the approaches needed to overcome these challenges in early drug discovery.

Antonia and Geoffrey provide valuable insights into some of the issues and opportunities in enzyme activation, which can be useful for researchers in the field. Join us as we explore this exciting area of drug discovery and gain insights from our experts in the field! 

Click here to read the latest articles in SLAS Discovery.